Associations of Ventricular septal defects

Ventricular septal defects are the most common cause of congenital heart disease. They close spontaneously in around 50% of cases. Non-congenital causes include post myocardial infarction. Atrial fibrillation is associated more with atrial septal defects.


Features
  • classically a pan-systolic murmur which is louder in smaller defects Complications 
  • aortic regurgitation* 
  • infective endocarditis 
  • Eisenmenger's complex 
  • right heart failure 
* aortic regurgitation is due to a poorly supported right coronary cusp resulting in cusp prolapse

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